The Six

The Six are, to simply put it, the six humans who were present in the Cabin. Isaac, Jib, Khaled, Jason, Andrew, and Alex. They have been together since the dawn of time and will likely persist until the eventual heat death of the universe, in which it is likely that their expeditions will carry on for eternity in some other universe. During the Night, each of the Six recognizes themself as one of these entities and cherishes their other friends.

SPOILERS

Once Takhim has taken over his vessel (Jib), he offers each of the other 5 a conversation before the end of the night. Each one of them gets to be awoken from sleep and hold a private conversation, in which they get to say their goodbye to the current expedition.

During the Nightmare Route, it is revealed that the Six are not really Six. Takhim is Jib's subconscious. Takhim was once mortal, but through some unspecified means he gained his omniscience. The other of the Six were Takhim's original friends who died. Death did not release them, as Takhim would capture their souls and engage in expeditions with them for the rest of eternity.

At least, that is until the events of the Nightmare Route. Khaled discovers the cycle. He initially cries tears of joy, an eternity spent with his friends?

And then he recognizes that he is not a member of the Six. He is a member of the current expedition, merely a manifestation of the spirit of a now unknown entity behind Khaled. There will only ever be one Khaled Messai who has lived the exact life. This realization that as he falls asleep, Khaled Messai will never return, is what leads to the event of the Nightmare Route.

Something important to note is that as the expeditions end, the worlds that they created do not. They persist forever, merely with the Six removed. See "expeditions" for more detail.